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NABP Exam NAPLEX Topic 2 Question 91 Discussion

Actual exam question for NABP's NAPLEX exam
Question #: 91
Topic #: 2
[All NAPLEX Questions]

How does pregabalin work in the treatment of seizures?

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Suggested Answer: B

Pregabalin works as a ligand of the auxiliary 2 subunit site of certain voltage-dependent calcium channels (VDCCs), and thereby acts as an inhibitor of 2 subunit-containing VDCCs.


by Steffanie at Sep 14, 2024, 10:23 PM

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Cassie
5 months ago
E, SV2A binder, that's the one! It's like pregabalin is the bouncer at the neuron's door, keeping the party under control.
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Thaddeus
6 months ago
GABA agonist, for sure. Pregabalin is like a virtual hug for your neurons, calming them down and preventing seizures.
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Karol
4 months ago
GABA agonist, for sure. Pregabalin is like a virtual hug for your neurons, calming them down and preventing seizures.
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Elroy
4 months ago
E) SV2A binder
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Afton
4 months ago
D) GABA agonist
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Huey
5 months ago
C) AMPA receptor antagonist
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Olga
5 months ago
B) 2 ligand
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Aide
5 months ago
A) Sodium channel blocker
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Chauncey
6 months ago
Hmm, I'm not sure. Maybe we should review the mechanism of action again.
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Corazon
6 months ago
I believe it's actually an SV2A binder.
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Chauncey
6 months ago
I think pregabalin works as a GABA agonist.
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Patti
6 months ago
Hmm, I thought it was an AMPA receptor antagonist. Guess I need to brush up on my pharmacology knowledge.
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Loreta
5 months ago
I guess we all need to review our pharmacology notes.
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Sheridan
5 months ago
I always thought it was an SV2A binder.
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Xochitl
5 months ago
Really? I thought it was a sodium channel blocker.
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Lynelle
5 months ago
I believe it works as a SV2A binder.
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Lelia
5 months ago
Really? I thought it was an AMPA receptor antagonist.
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Rosamond
5 months ago
It's actually a GABA agonist.
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Ligia
5 months ago
It actually works as a GABA agonist.
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Cyndy
6 months ago
I'm pretty sure it's a 2 ligand, so B is the right choice. It binds to a specific receptor that helps regulate neuronal activity.
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Lucy
6 months ago
Pregabalin is a GABA agonist, so D is the correct answer. It enhances the inhibitory effects of GABA in the brain, leading to reduced neuronal excitability and seizure control.
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Bobbye
5 months ago
That's correct. It's important for treating seizures in patients.
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Merlyn
5 months ago
So, it helps reduce neuronal excitability and control seizures.
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Stevie
5 months ago
Yes, you're right. Pregabalin works by enhancing the inhibitory effects of GABA.
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Tracie
5 months ago
I think the answer is D) GABA agonist.
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