Deal of The Day! Hurry Up, Grab the Special Discount - Save 25% - Ends In 00:00:00 Coupon code: SAVE25
Welcome to Pass4Success

- Free Preparation Discussions
Mail Us support@pass4success.com
Location US
Mob_nav_barsMENU

NABP NAPLEX Exam - Topic 10 Question 81 Discussion

Actual exam question for NABP's NAPLEX exam
Question #: 81
Topic #: 10
[All NAPLEX Questions]

Which of the following is true regarding extent of absorption of drugs?

Show Suggested Answer Hide Answer
Suggested Answer: A

The dihydropyridine drug -- nifedipine -- is the active ingredient found in the medicine Adalat. Nifedipine is used to treat angina, Reynaud's phenomenon and hypertension. It is also used as a tocolytic agent in premature labor.


by Yoko at May 09, 2024, 07:01 AM

Limited Time Offer

25%

Off

Get Premium NAPLEX Questions as Interactive Web-Based Practice Test or PDF

Contribute your Thoughts:

0/2000 characters
Submit Cancel
Celia
5 months ago
B is misleading, lipophilic drugs can cross membranes, just slower.
upvoted 0 times
...
Brittni
6 months ago
Wait, grape juice affects drug absorption? That's surprising!
upvoted 0 times
...
Elbert
6 months ago
C makes sense, hydrophilic drugs struggle with that water layer.
upvoted 0 times
...
Paola
6 months ago
I disagree with D, P-glycoprotein actually reduces absorption.
upvoted 0 times
...
Tracey
6 months ago
A is definitely true, absorption can be incomplete.
upvoted 0 times
...
Kenneth
7 months ago
I vaguely remember something about P-glycoprotein, but I thought it was more about limiting absorption rather than enhancing it. So, I’m unsure about option D.
upvoted 0 times
...
Verdell
7 months ago
I practiced a question similar to this, and I recall that hydrophilic drugs struggle with crossing membranes due to their solubility issues. So, option C seems plausible.
upvoted 0 times
...
Alfred
7 months ago
I'm not entirely sure, but I think lipophilic drugs can actually cross cell membranes. Isn't that why they are often more bioavailable?
upvoted 0 times
...
Natalie
7 months ago
I remember that oral drug absorption can be incomplete, especially with certain formulations. So, I think option A might be true.
upvoted 0 times
...
Stephen
7 months ago
Alright, let me review what I know about lipophilicity, hydrophilicity, and transporters like P-glycoprotein. I think I can narrow this down.
upvoted 0 times
...
Tomoko
7 months ago
Okay, I know the basics of drug absorption, so I should be able to figure this out.
upvoted 0 times
...
Cassi
7 months ago
Hmm, I'm a bit unsure about the details of drug absorption. Let me think this through carefully.
upvoted 0 times
...
Scarlet
7 months ago
This question seems straightforward, I think I can handle it.
upvoted 0 times
...
Emily
7 months ago
Ugh, I'm not too confident in my pharmacology knowledge. This is going to be tricky.
upvoted 0 times
...
Denny
7 months ago
The Form-Based Composer seems like it could work, but I'm not confident that it would provide the level of control and customization needed for this type of test.
upvoted 0 times
...
Alesia
7 months ago
I think the answer is True, but I'm a bit uncertain. I'll make a note to research this topic more before the exam to solidify my understanding.
upvoted 0 times
...
Nan
8 months ago
Okay, let me think this through. The question is asking about the first program the Linux kernel starts at boot time using System V init. That means it's likely going to be one of the standard init-related paths, not something more obscure. I'm going to go with /sbin/init as my best guess.
upvoted 0 times
...
Adell
1 year ago
Option E is just plain funny. Grape juice as a drug absorption inhibitor? Maybe they should add wine as a choice too, for a more 'spirited' exam experience.
upvoted 0 times
Whitley
11 months ago
C) Drugs which are too hydrophilic are not soluble enough to cross the water layer adjacent to the cell
upvoted 0 times
...
Keneth
11 months ago
B) Drugs which are too lipophilic cannot cross the lipid cell membrane
upvoted 0 times
...
Brandon
12 months ago
A) After oral ingestion of drugs, the absorption of drug may be incomplete
upvoted 0 times
...
...
Haydee
1 year ago
D is incorrect. P-glycoprotein is an efflux transporter that actually reduces drug absorption, not enhances it. Grape juice inhibiting P-glycoprotein could potentially increase drug absorption, not decrease it.
upvoted 0 times
...
William
1 year ago
I'm not sure about B and C. Shouldn't the drug's physicochemical properties be balanced to achieve optimal absorption? Maybe I need to review my lipophilicity and hydrophilicity concepts.
upvoted 0 times
Willie
11 months ago
User 4: D) P-glycoprotein is an efflux transporter which is present in the enterocytes and it enhances the absorption of drug
upvoted 0 times
...
Ciara
11 months ago
User 3: I'm not sure about B and C. Shouldn't the drug's physicochemical properties be balanced to achieve optimal absorption? Maybe I need to review my lipophilicity and hydrophilicity concepts.
upvoted 0 times
...
Dortha
12 months ago
User 2: E) Grape juice activates P-glycoprotein leading to substantial inhibition of absorption of drugs
upvoted 0 times
...
Royce
1 year ago
User 1: A) After oral ingestion of drugs, the absorption of drug may be incomplete
upvoted 0 times
...
...
Lourdes
1 year ago
I agree with A. Incomplete absorption is a common phenomenon, and it's crucial to understand the factors affecting it, like you mentioned.
upvoted 0 times
Kent
1 year ago
User 2: Yeah, it's important to consider factors affecting absorption.
upvoted 0 times
...
Asuncion
1 year ago
User 1: I think A is true, incomplete absorption happens often.
upvoted 0 times
...
...
Zoila
1 year ago
Option A is correct. Drug absorption can indeed be incomplete after oral administration due to various factors like first-pass metabolism, drug efflux transporters, and physicochemical properties of the drug.
upvoted 0 times
...
Murray
1 year ago
That's a good point, but I still think A is more likely based on what I've studied.
upvoted 0 times
...
Gail
1 year ago
I disagree, I believe B is true because lipophilic drugs have difficulty crossing cell membranes.
upvoted 0 times
...
Murray
1 year ago
I think A is true because some drugs are not fully absorbed after oral ingestion.
upvoted 0 times
...

Save Cancel