NABP Exam NAPLEX Topic 10 Question 49 Discussion

Actual exam question for NABP's NAPLEX exam

Question #: 49
Topic #: 10

[All NAPLEX Questions]

Which H2-receptor blocker may cause gynecomastia in men due to its antiandrogenic effects?

ARanitidine

BNizatidine

CCimetidine

DFamotidine

Show Suggested Answer

Suggested Answer: C

Cimetidine has multiple drug interactions due to its inhibitory effects on CYP1A2, 2C9, 2D6, and 3A4. Inhibition of these enzymes can cause an increase in the serum concentrations of drugs metabolized by these enzymes, leading to toxicity.

by Merlyn at Jul 26, 2022, 04:03 PM

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