NABP Exam NAPLEX Topic 1 Question 20 Discussion

Actual exam question for NABP's NAPLEX exam

Question #: 20
Topic #: 1

[All NAPLEX Questions]

What indication usually requires higher dose of proton pump inhibitor?

AHelicobacter pylori

BEsophagitis

CDuodenal ulcer

DStress ulcer prophylaxis

EZollinger-Ellison syndrome

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Suggested Answer: E

The diagnosis of Zollinger-Ellison syndrome is suggested when plasma gastrin is > 1000 pg/ml and the basal acid output is > 15 mEq/h or when associated with a pH < 2. The treatment is focused on controlling gastric acid hypersecretion and localisation of the tumour and its metastases. Proton pump inhibitors are the most effective antisecretory drugs and can be administered at high dosages

by Earleen at May 07, 2022, 07:31 PM

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