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NABP Exam FPGEE Topic 2 Question 85 Discussion

Actual exam question for NABP's FPGEE exam
Question #: 85
Topic #: 2
[All FPGEE Questions]

Mechanism of action of doxorubicin is:

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Suggested Answer: E

by Marge at Jun 28, 2024, 05:02 PM

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Eun
2 months ago
Wait, doxorubicin is an alpha blocker? That's just ridiculous. I'm going to have to go with the classic topoisomerase II inhibitor, A.
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Belen
1 months ago
I've also heard that doxorubicin works by inhibiting topoisomerase II. It's a well-known mechanism for this drug.
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Marge
2 months ago
Yeah, A is the correct answer. It's a common mechanism of action for doxorubicin.
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Lashandra
2 months ago
I agree, doxorubicin is definitely not an alpha blocker. Topoisomerase II inhibition makes more sense.
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Catarina
2 months ago
Hmm, allosterically enhancing GABA? That's just silly. This is clearly a cancer drug, not a central nervous system one. A has got to be the right answer here.
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Mona
2 months ago
Haha, beta antagonist? What is this, a cardiovascular exam? Definitely not D. I'm going to go with the topoisomerase II option, A.
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Audrie
20 days ago
Good choice, A is the correct answer for the mechanism of action of doxorubicin.
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Mel
21 days ago
Definitely not D, that's for sure. A is the right choice.
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Marlon
2 months ago
Yeah, that's right. Doxorubicin works by inhibiting topoisomerase II.
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Kimbery
2 months ago
I think A is correct, it inhibits topoisomerase II.
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Chun
2 months ago
Wait, isn't doxorubicin an antitumor antibiotic? I think it's got to be something related to DNA or protein synthesis. C - inhibits peptidyl transferase seems more plausible.
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Lashandra
3 months ago
Doxorubicin is a chemotherapy drug, so it's got to be inhibiting something important for cancer cells. I'm going with A - inhibits topoisomerase II. Sounds like the right mechanism to me.
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Dick
29 days ago
User4: Yeah, A) makes sense for a drug like doxorubicin
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Noelia
1 months ago
User3: I'm not sure, but I'll go with A) too
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Wilburn
2 months ago
User2: I agree, that seems like the right mechanism for a chemotherapy drug
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Sherell
2 months ago
User 2: Yeah, that makes sense for a chemotherapy drug.
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Annice
2 months ago
User 1: I think it inhibits topoisomerase II.
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Justine
2 months ago
User1: I think it's A) Inhibits topoisomerase II
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Nickolas
3 months ago
I'm not sure, but I think the correct answer is A) Inhibits topoisomerase II based on what I've studied.
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Steffanie
3 months ago
I agree with Jenelle, because doxorubicin is known to inhibit topoisomerase II which leads to DNA damage.
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Jenelle
3 months ago
I think the mechanism of action of doxorubicin is A) Inhibits topoisomerase II.
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